A numerical rating scale (NRS 0: no itch 10 points: worst imaginable itch) was utilized to assess maximal values of itch intensity both in the last 3 days and during the course of the tumor. The main clinical parameter, the presence of itching, was documented, including the affected anatomical locations. All BCCs were divided into the following clinical types: nodular, superficial, morphoeic, and ulcerated. Individuals with itch constituted a group for further detailed analysis.Īfter inclusion, detailed information on demographics, clinical history, and physical findings was recorded. All patients in our study group were Caucasians. The age range of studied individuals was 17–95 years (mean: 70.5 ± 11.9 years). Therefore, the final study group constituted 180 patients (83 women and 97 men) with histologically confirmed BCC. Those patients were excluded from the study. Among 191 patients, 11 subjects’ histopathology revealed lesions other than BCC. After the surgery, the lesions were verified with histopathology. Exclusion criteria included: mental status changes making the patient unable to make a detailed assessment of itch, known severe renal or liver disease, or a history of chronic dermatological or psychiatric diseases. The inclusion criterion was BCC as the initial primary clinical diagnosis. Twenty patients refused participation in the study without specifying the reasons (response rate: 90.5%). We approached 211 consecutive patients above the age of 17 who were surgically treated in the Dermatosurgery Unit with the clinical diagnosis of BCC. Written informed consent to participate was obtained from all patients before enrollment, and they were also informed of their right to leave the study at any time. The study procedures were carried out in agreement with the Helsinki Declaration of 1964 and its later amendments, and good clinical practice guidelines. The project was approved by the local Ethical Committee (ST.C260.18.019). The material for the study was collected between September 2017 and December 2019.
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